CeraVe Vs. Cetaphil: Which Is Better for Sensitive Skin? I Tested Both to Find Out.
Dermatologists have some pretty strong opinions...

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You know what my dermatologist says anytime I have a skin flare-up? She tells me I need to go back to the basics, and usually, that means products from CeraVe or Cetaphil. If you have super sensitive skin or are dealing with any sort of skin irritation—hi eczema and rosacea—you've also probably been given this same directive. These drugstore skincare brands have amassed a cult-like following for their simple and affordable formulas that are gentle enough for even the most reactive skin types. But how do you possibly choose one? Can you use both? Is one better than the other?
To settle this debate, I consulted dermatologists and conducted my own little experiment to come up with a definitive answer. I completely swapped out my skincare routine, exclusively using CeraVe for one week and Cetaphil for the next (then switching things up and using both on half of my face for *funsies*). I tried a cleanser, vitamin C serum, moisturizer, and sunscreen from each line to compare the formulas, textures, and packaging, as well as how each product made my skin look and feel. Let me tell ya, my skin needed a refresh and going back to the basics has me looking extra radiant. Soooooo... does that mean we have a clear winner? Keep reading to find out which drugstore brand is the best option for your skin.
So what is CeraVe?
While I’m sure you’ve seen CeraVe while perusing your local CVS, I bet you discovered it on TikTok—or maybe your dermatologist recommended it to you. CeraVe is still a relatively fresh brand (especially compared to Cetaphil below). It launched in 2005 with just three products—the Moisturizing Cream, Moisturizing Lotion, and Hydrating Cleanser.
Dermatologists helped develop CeraVe because they noticed many skin issues (like acne, eczema, psoriasis, dryness, etc.) were caused by a compromised skin barrier. So, to restore the barrier—and remedy these issues—CeraVe formulas feature three essential ceramides (AKA lipids that form the skin’s barrier and help it function) that mimic the ones naturally found in your skin.
CeraVe’s lineup now features a slew of derm-favorite products, including a retinol serum, SPF moisturizer, and hydrating foaming cleanser, along with an array of sunscreens that all restore and maintain the skin’s barrier function. Even with all the additions, the OG Moisturizing Cream and Lotion remain cult-classics because they “provide intensive hydration and restore the skin’s natural moisture balance, thanks to their ceramide and hyaluronic acid content,” says dermatologist Mona Foad, MD.
And...what is Cetaphil?
A cool thing about Cetaphil? Your grandparents probably used the brand growing up. Founded in 1947, Cetaphil's main focus has always been crafting gentle products specifically for sensitive skin. The formulas are as basic as they come, mostly comprised of lightweight hydrators like hyaluronic acid, glycerin, and panthenol, all made without fragrance.
You can go all the way back to Cetaphil's ~humble~ beginnings, because the brand’s first ever product—the Gentle Cleanser—is still available (and loved) today, especially by dermatologists like Geeta Yadav, MD. She also says the brand’s wide range of cleansers are some of the best of all time. “There are options to address a variety of concerns, including everything from rough texture to excess oil," she adds.
Of course, Cetaphil has expanded far past the original cleanser now. They also make moisturizers, serums, sunscreens, and body products, including the extra delicate Vitamin C Serum and Exfoliating Rough & Bumpy Cream.
What are the main differences between CeraVe and Cetaphil?
Just by looking at the two brands, they’re pretty darn similar. You can find them both at your local drugstore, the prices are almost identical, and even the packaging kinda matches (twins?!). Dr. Foad also mentions that every formula from both brands is made without fragrance and designed to minimize irritation. However, when you get into the nitty gritty, Cetaphil and CeraVe greatly differ from one another. “Cetaphil was founded specifically to address the needs of sensitive skin, while CeraVe specializes in skin barrier support,” explains Dr. Yadav. So what does this mean for you exactly?
Well, “CeraVe contains ceramides, which are essential for restoring and maintaining the skin's natural barrier, along with hyaluronic acid, which attracts moisture to the skin," explains Dr. Foad. "This makes CeraVe particularly effective for individuals with dry or compromised skin, as well as conditions like eczema or rosacea,” she adds. However, Cetaphil “uses simpler ingredients such as glycerin and panthenol to gently hydrate your skin without overwhelming it," she notes. Because of this, she says Cetaphil is great for people with extremely sensitive or reactive skin that's prone to irritation and inflammation from other products.
Is Cetaphil or CeraVe better for sensitive skin?
This is a verrrry tough question, because truthfully, they’re both stellar options for sensitive skin. Digging deeper, each brand performs a little better for different types of sensitive skin. I know it sounds complicated, let me explain.
Does your sensitive skin lean dry, or do you struggle with eczema? Try CeraVe, says Dr. Foad, since it's formulated with moisturizers that'll help actually pull hydration into your skin. On the other hand, if your skin is oily, acne-prone, or just plain sensitive, opt for Cetaphil. “Cetaphil’s lightweight, non-comedogenic formulas hydrate without irritating or clogging pores, making it a good choice for those looking for a simple, effective skincare routine,” says Dr. Foad. “Ultimately, both brands offer high-quality products, but the decision should be based on your skin type and concerns,” she adds.
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